For patients, recent stroke, it is useful to listen to music

October 7, 2008

For patients, recent stroke, it is useful to listen to music
It can not only improve mood, but also to accelerate the recovery of memory and attention, disturbed as a result of the disease, reported the journal Brain.

Scientists from the University of Helsinki conducted a study involving 60 patients with newly stroke. All have suffered from violations of traffic regulations and disorders of cognitive functions such as memory and concentration. Patients are divided into three groups: some of them suggested a day for several hours listening to your favorite music, others - to listen to audio books, the rest did not hear anything. Also, all patients conducted in the standard therapy for stroke.

It turned out that people who listen to music, the recovery of memory and attention have been noticeably better, and their mood was more positive. In particular, three months after their stroke, verbal memory (RAM, focused on memorizing words) improved by 60%. In comparison, patients, listens audio book, this figure increased by 18%, while the control group - 29%, reported leader of the study Teppo Sarkamo.

According to Finnish scientists, mud wraps can complement current methods of rehabilitation for patients with stroke. This method is cheap and available, and may be appointed earlier than other treatments.

Amino acids help to recover quickly under stress

Amino acids help to recover quickly under stress
The aim of the recent research of Dr. Nicholas Ratamess and colleagues has been checking the effects of amino acids at the reception muscle strength, power and endurance during a short training high overloads using weight. There have been picked by two groups of volunteers (a group of amino acids and placebo), who took part in the training program, which implies high-training for four weeks and a reduction in quantity / frequency of training over the next two weeks.

The first phase consisted of two weeks of moderate-intensity, vysokoobemnyh training with aggravated and the two-week training. Indeed overload achieved daily training the entire body, which minimized the extent of recovery between sessions. Every two weeks, scientists recorded rates of force, power and high endurance.

Subjects amino acid group consumed the entire 0.4 grams of amino acids for each kilogram of body weight every day, dividing them into three receive. In addition, each was instructed to take amino acids separately from food - an hour before or two hours after .. The participants received placebo group exactly the same instructions. According to the authors’ experiment, none of the actors did not take any medicines, other nutritional supplements or anabolic funds, which could distort the results of observations.

It was found that the rate of one repetition maximum (1PM) in squatting and lying press within a week of training has fallen in the placebo group, a group similar to amino acid changes were observed. After the second week of exercises in the placebo group 1PM to curtsey and left at the same level as in the meantime, amino acid group markedly increased. Peak power of ballistic lying press has increased significantly in the placebo group after the second week of the training protocol, a group of amino acids such changes were reported. After the fourth week in the placebo group ratio of peak power in ballistic lying press not changed, but the amino acid group was marked by a trend towards recovery.

Thus, amino acids accelerate recovery in stressful situations, whether strenuous training or any other physical or emotional overload.

Scientists from the U. S. were able to cure hemophilia in mice

Scientists from the United States were able to cure hemophilia in mice
Scientists from the Medical College of Albert Einstein at the eshiva University found that the development of hemophilia A defect linked to the endothelial cells of the liver. Transplanted donor cells from a healthy animal, they were able to cure hemophilia in mice, reported Journal of Clinical Investigation.

Haemostasis - inherited disease in which any damage was caused severe and prolonged bleeding due to broken blood coagulability. The most frequent form of haemophilia - hemophilia A - due to the lack or inadequacy of the so-called factor VIII in blood plasma.

Previously it was thought that Factor VIII is produced hepatocytes - cells that make up the bulk of the liver and perform most of its functions. But scientists under the leadership of Sanjeev Gupta suggested that for formulating a factor VIII responsible sine capillary endothelial cells of the liver. To confirm their theory, they conducted experiments on animals.

Using a substance called monokrotalin they had destroyed their endothelial cells liver, hemophiliacs A. Then, in the vein flowing in the liver, imposed endothelial cells taken from healthy donor mice.

«Three months after the transplantation of livers of mice in the study, we found that the transplanted cells prizhilis and their number increased. Even more importantly, the mice with transplanted cells began to produce Factor VIII in sufficient quantity to fully correct haemophilia A », - said the author of the study Antonia Follenzi.

A hemophiliacs suffer one of the ten thousand men. Current methods of combating hemophiliacs are not sufficiently effective. Opening of the American scientists could lead to new treatments, but raise the question of testing on humans was premature. Currently, experts are seeking alternatives krotalinu, which is considered a toxic drug.

Ultrasound helps immunity to fight cancer

September 1, 2008

The intensive ultrasonic radiation aimed at malignant tumor and causing it to vibration can be an effective method of cancer treatment, reported in the press release Duke University in Durham, North Carolina. With such impact of a patient’s own immune system begins to destroy tumor and metastases.

Results of work carried out by engineers and oncology at Duke University, were published in the Journal of Translational Medicine. Supervised study Zhenlin Hu, is currently working in the Second Military Medical University in Shanghai.

Focusing high-intensity ultrasound radiation (High-intensity focused ultrasound, HIFU) has been studied and used for the treatment of malignant neoplasms in Europe, USA and China. Thus far, however, apply such its intensity, which kills cancer cells, heating them.

Unlike principal work of American researchers that seeks only a matter of ultrasound vibrations tumor, violating the integrity of its cell membranes. In doing so, cellular content, containing many antigens, enters the bloodstream. The immune system recognizes these antigens and produce clone of the antitumor lymphocytes that recognize and destroy the primary tumor as well as its metastases, regardless of their location.

According to Professor Pei Zhong, which was conducted in the laboratory study, mechanical ultrasonic radiation was not as effectively as temperature, for the direct destruction of cancer cells, but caused more than twice as strong immune response in laboratory mice, colon cancer patients. It seems that this is due to the fact that when the mechanical impact in the blood falls far greater variety of antigens.

If the results of the experiment are confirmed in humans, this technique can effectively treat cancer without prompt treatment. This is especially true in treating patients with metastases in such important organs as the brain and lungs, surgical intervention which is difficult.

Recall that in the body of any human being formed thousands of cancer cells a day, but normally they are recognized and destroyed immune system. If the antitumor immunity one of these cells by uncontrolled division develops in malignant tumors. Particles of this tumor with a current separation of blood to other organs, creating metastases. As the American study, stimulation of cancer antigens can restore the antitumor activity of the immune system.

Products and spices can weaken the pain

Pain diet starts emerging. We explain that the root crops, vegetables and spices, activates cell receptors, causing pain, quite a lot. Their action is expected, is that gradually, one meal after another, they increase the resilience of the individual threshold.

After severe red pepper (kapsaitsin - molecule, which activates a particular receptor: Trpv1) is wasabi horseradish. Root of the Japanese plants, which is part of the spices to raw fish (sushi), is a stimulant for another pain receptor (wasabi receptor: Trpa1). In the same way as horseradish, there are garlic, cinnamon, mustard, mustard oil. Unwanted, but very pleasant for connoisseurs effects, manifested in the use of these products - is painful effect on the channels of peripheral nerve cell membranes: kapsaitsina feed and feed wasabi. Eyes begin to tears, throat compressed, there tingle … cells get momentum like sms: “Anxiety, attacks us something malicious.” After a nervous way signal reaches the brain, which favours command: activated immune protection against invasion, ANTIPYRETIC molecules and endorfiny (obezbolivatel natural organism).

About kapsaitsina receptors has long been known, and in the United States of drugs based on molecules of acute red pepper already in the Phase III clinical trials on human beings at the nevropaticheskih pain and fever, entitled “St. Anthony’s fire.” This drug will be influenced and some types of wanton pain, which seems to arise from the “memory”, registered at the nerve level. As phantom pain syndrome in humans, underwent amputation: no legs, but it is sore. And now become aware of the new receptor, wasabi, which is activated in the case of oxidative stress (for example, regarding the effects of free radicals, increase in the skin under the influence of the sun: in other words, the sense of “pressing” pain), or by reason of such species pollution as smoke or passive smoking in the city was able to (burning in the eyes, throat, cough). About It tells the publication in the Internet edition of the authoritative American scientific journal Proceedings of the national academy of sciences (Pnas) Labour group of scientists Medical School University of Florence. What is their opening? The new transfer mechanism of pain, which paves the way for a more detailed knowledge of how activated negative momentum (pain) and how it is suppressed.

The Florence study indicates a path of intensifying pain, independent of the road, activated protoglandinami (inflammation), to which, as you know, aspirin or blocked Fans. Scientists have found that a molecule 4 - gidroksinenala produced by the body only in extreme situations (burns, inflammation or even free radicals oxidative stress), is a powerful incentive, causing pain receptors through Trpa1 (exactly wasabi) on the surface of neurons.

Perandzhelo Dzheppetti, director of the Center tsefalgii University of Florence, coordinated the study, which was attended by scientists from the University of California. Dzheppetti explains: “Now we will work towards the creation of innovative drugs, possessing properties aimed at reducing acute or chronic pain by blocking action 4 - gidroksinonenala receptors on Trpa1. This will be a new class of medicines effective against those types of pain (nevropaticheskih, cancer, gemikranii and pain caused by inflammation), which could not lift with the help of modern analgesics.

But the beginning of the road could become a menu that can raise the pain threshold of portability. And, here’s a surprise, tradition coincides with knowledge: burning pepper, garlic, horseradish, ginger many centuries been used as medicine for the peoples living in extreme natural conditions and working in extremely difficult conditions. Wasabi, in contrast, came from traditional culture, in which resistance to pain is one of the pillars of honor: samurai people live on the rules, to follow that wasabi is needed.

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